I don’t think so because the base size won’t change, we’ll still need to enter it and it will still serve the same purpose as the size from which other sizes are calculated from.
Which brings me to something else that has bothered me forever…
I really see no point in the sizes being constrained in the pattern preferences. Shouldn’t this be constrained in the measurement chart - since it’s the measurement chart that will only cover a certain number of sizes?

(This could be automatically set by the Base and End sizes drawn from the measurement chart loaded.)